Such a nice read, and the point on mitochondrial decline is the one that many miss entirely. Reactive oxygen species building up because mitochondria are inefficient is the mechanism behind the brain fog and low energy that gets blamed on stress or ageing by default. Worth noting that chronic high cortisol accelerates several of these processes simultaneously, inflammation, insulin resistance, and immune decline included, which is probably why a stressful job feels like it ages people faster than the calendar does, thanks for sharing this..
Great advice that we have known instinctively, viscerally for a very long time before the science ran the experiments that proved it. Eat well, exercise, learn, socialize and sleep. The difficulty lies in doing it in a society that bombards us from birth with incessant messaging to do otherwise or risk missing out on the good life. Until we accept and teach our children a different, simpler, understanding of what a good life looks like a very large percentage of people are going to remain caught up in patterns that are incompatible with long term health. Unfortunately, the consumption machine that fuels everything that we take for granted in our modern world needs us not to do that. The house of cards that is our economy collapses if we do. Catch-22.
Absolutely agree - the hardest part isn’t knowing what to do, it’s actually living it out in modern environments that pull us in the opposite direction.
Such a nice read, and the point on mitochondrial decline is the one that many miss entirely. Reactive oxygen species building up because mitochondria are inefficient is the mechanism behind the brain fog and low energy that gets blamed on stress or ageing by default. Worth noting that chronic high cortisol accelerates several of these processes simultaneously, inflammation, insulin resistance, and immune decline included, which is probably why a stressful job feels like it ages people faster than the calendar does, thanks for sharing this..
Thanks for this insight too
Great advice that we have known instinctively, viscerally for a very long time before the science ran the experiments that proved it. Eat well, exercise, learn, socialize and sleep. The difficulty lies in doing it in a society that bombards us from birth with incessant messaging to do otherwise or risk missing out on the good life. Until we accept and teach our children a different, simpler, understanding of what a good life looks like a very large percentage of people are going to remain caught up in patterns that are incompatible with long term health. Unfortunately, the consumption machine that fuels everything that we take for granted in our modern world needs us not to do that. The house of cards that is our economy collapses if we do. Catch-22.
Absolutely agree - the hardest part isn’t knowing what to do, it’s actually living it out in modern environments that pull us in the opposite direction.
even as a biochemist myself i had not heard of endothelium dysfunction before!! these articles never fail to teach me something new.